Desk of Dr. James A. Hayward
Chairman, President & CEO of Applied DNA Sciences
We hope our May newsletter find you and your family healthy and well. Much has happened since April, so we wanted to give you an update on our COVID19 developments as we all work together to get our communities back on track and back to business.
Applied DNA is one of the only companies engaged BOTH in the detection of the virus and in its prevention. The diagnostic assay is designed to be run in high-throughput workflows that enable same-day results to be transmitted to the ordering physician. In a spirit of continuous innovation and improvement of the end-to-end process of patient diagnosis, the Company is investigating methods to enhance the assay to increase the ease of patient sampling by using saliva instead of invasive nasopharyngeal swabbing methods. Both aspects of the Company’s COVID-19 platform (detection and prevention) target the protein (and its viral gene) that enables the virus to gain entry into human cells.
- As a complement to the diagnostic kit, the Company’s candidate vaccines use engineered (by partner Takis Biotech in Rome) synthetic portions of the S gene to present the antigens of the protein to the patient’s immune system, hopefully eliciting the generation of antibodies that recognize and help clear the virus from the patient, and neutralize the ability of SARS-CoV-2 to infect human cells. Early results announced earlier this month, suggest that the vaccine candidates do so in test animals. The pre-clinical and clinical trial plan calls for utilizing Applied DNA’s novel DNA platform of linear DNA.
- We recently received U.S. Food and Drug Administration (FDA) Emergency Use Authorization (EUA) for our Linear™ COVID-19 diagnostic candidate to detect SARS-CoV-2, the novel coronavirus that causes the disease COVID-19. Validation for the EUA was completed in collaboration with Stony Brook University Hospital; the company’s neighbor and collaborator on campus.
We are grateful for the support of our families, friends and colleagues around the world. Innovation is truly a collaborative process, and we are looking forward to seeing our economy open safely and in good time.
Be well and Be safe,
James A. Hayward
Chairman, President & CEO
Up Close: In Conversation with Applied DNA Sciences’s MeiLin Wan
Which other industry has the best handle on the supply chain?
We don’t believe there is any one industry that has the best handle on supply chains. Working in closed loop supply chains for the past six years, we know that partners that have tight controls, coupled with systematic authentication and testing of fiber, yarn and fabrics, are far ahead of others that have little to no control of their raw materials. It comes down to having good systems, with track-and-trace on the physical product itself.
What can apparel learn?
If you “claim it,” you “own it.” Transaction-based systems—including blockchain—do not preserve the integrity of the actual material itself, and therefore, you cannot know with certainty if the product stays pure and undiluted in the finished product. The most important learning is that you have to protect the raw materials and ensure they do not get adulterated or mixed with materials that are not meant to be there.
NutraIngredients 2020 USA Awards
How to make sure your cannabis is the real deal
by John Shearman
May 4, 2020
This same question is asked by many consumers across various categories of products we consume everyday. Do I really know the chicken I’m about to buy is raised on a free-range farm? Is the medicine I’m about to take authentic? Is the fish I’m planning to eat for dinner from Boston as advertised?
We all want to know the origin of products, their claims, what are the ingredients, was it produced using Current Good Manufacturing Process (cGMP) best practices, as well as adherence to Federal and State regulations. Many brands today have implemented strategies and initiatives to ensure they can answer these questions for their customers with open transparency, traceability of facts and trust through sharing provable authentic data.
Read more at Cannabis Business Executive
Waving Goodbye to the Handshake: 7 Alternatives
to a Workplace Custom
By John Egan | April 27, 2020
The time-honored handshake spreads goodwill in the workplace—in job interviews, at staff meetings and during other face-to-face interactions. But the handshake also spreads germs.
During the coronavirus pandemic, handshakes have given way to fist bumps, elbow taps and other greetings that eliminate hand-to-hand contact but don’t necessarily decrease transmission risks associated with coronavirus. Once people start filtering back to workplaces in great numbers, will they shake hands again?
Read more at SHRM.org
Stay Safe! A cuddly reminder from across the pond
Our friend and long-time collaborator, UK-based Dr. Barbara Brockway (pictured with Bramley Bear), would like to send a friendly reminder to mask up and stay safe!
The flawed ways brands talk about sustainability
BY ALDEN WICKER | 16 APRIL 2020
Companies are busy announcing sustainability initiatives, but even experts don’t know what’s real and what’s fake.
In August, the Norwegian Consumer Authority called H&M out for greenwashing.
H&M’s Conscious collection was made out of more sustainable materials like organic cotton, recycled polyester and Tencel. The problem was that H&M didn’t explain how, exactly, these materials are better for the environment.
“What do the brands mean when they are talking about something that has a reduced impact?” says Maxine Bédat, founder of the New Standard Institute, which pushes brands to disclose their environmental and social footprint. “Have they measured it? If they haven’t, we shouldn’t trust it.”
While a leader in the market, it’s unclear why H&M was targeted by the government agency when few brands back up their sustainability claims.
I would probably be a lot richer if I took on all the clients that want to talk about sustainability. But I don’t want to do the greenwashing,” says Emelie Gintzburger Akerbrant, an independent sustainable fashion communications advisor. “There is so much noise and so much happening around sustainability. We don’t know what’s real and what’s fake.”
Read more at Vogue Business
You Don't Know What You Don't Know
Headlines like “How a stockpile of 39 million masks was exposed as fake” are one of many examples of how easy it is to infiltrate a supply chain, damaging the reputation of a brand, and putting the lives of healthcare workers and the general public at risk. The rapid increase in counterfeit PPE products has been under the watchful eye of Interpol, who seized 34,000 counterfeit and substandard masks, “corona spray”, and “corona medicine” with 121 arrests worldwide and seizure of potentially dangerous pharmaceuticals valued at 14 million USD.
“You don’t know what you don’t know,” stated Wayne Buchen, vice president of strategic sales at Applied DNA Sciences. “Most of the raw materials and inputs used to produce PPE are outsourced to low-cost suppliers in Asia. The United States is very dependent on obtaining raw materials from overseas. We do not have enough raw materials at home to make the volume of masks needed. With that in mind, how do you know that you are getting authentic PPE masks? The point is, you don’t.”
To be sure, CDC has identified many instances of counterfeit respirators and examples of misrepresentation of NIOSHapproved products, such as this example of a counterfeit respirator mask and box using Shanghai Dasheng Health Products Manufacture Co. Ltd.’s (SDH) NIOSH approval number, TC-84A-4329, without their permission. Please note these respirators have ear loops. The NIOSH-approved SDH model does NOT have ear loops. These respirators are not NIOSH approved. (3/31/2020)
While the CDC and other agencies are doing their best to identify counterfeits on their website, inevitably given the scale of the number of masks required, unapproved PPE may still find its way into the USA illegally.
U.S. Tags Amazon Sites as ‘Notorious Markets’
The e-commerce giant claims the attack is politically motivated
An Amazon facility in France. Amazon’s web domain there was one of the ones that landed on the U.S.trade representative office’s list of ‘notorious markets.’
PHOTO: THOMAS SAMSON AGENCE FRANCE PRESSE GETTY IMAGES
By William Mauldin and Alex Leary
WASHINGTON—The Trump administration accused Amazon.com Inc. of tolerating counterfeit sales on its online platforms in foreign countries, prompting the e-commerce giant to respond that the hit was politically motivated.
The U.S. trade representative’s office on Wednesday put Amazon’s web domains in Canada, France, Germany, India, and the U.K. on its “notorious markets” list of platforms that are believed to facilitate intellectual-property violations.